Comparison of Serum Zinc Levels Measured by Inductively Coupled Plasma Mass Spectrometry in Preschool Children with Febrile and Afebrile Seizures
نویسندگان
چکیده
BACKGROUND Changes in levels of trace elements have been proposed to underlie febrile seizures. Particularly, low zinc levels have been proposed as related factor of febrile seizure. In this study, we investigated whether mean serum zinc levels differed between children with febrile seizure and afebrile seizure. METHODS Using inductively coupled plasma mass spectrometry, serum zinc levels were measured in 288 children who had been diagnosed with febrile seizures (N=248) and afebrile seizures (N=40). Mean serum zinc levels were compared between the 2 groups. RESULTS Mean serum zinc level was 60.5±12.7 µg/dL in the febrile seizure group and 68.9 ±14.5 µg/dL in the afebrile seizure group. A significant difference in serum zinc levels was observed between the febrile and afebrile seizure groups (P<0.001). CONCLUSIONS Zinc levels in children with febrile seizure were significantly lower than those in children with afebrile seizure.
منابع مشابه
بررسی رابطهی بین سطح روی سرم وتشنج ناشی از تب در کودکان بستری دربیمارستان ولیعصر(عج) زنجان
Background and Objective: Febrile seizures (FS) are the most common seizures seen in childhood with a prevalence of 2-14% in different societies. This study was carried out regarding the possibility of the relationship between serum zinc levels and occurrence of FS. Materials and Methods: 117 children ranging from 6 months to 5 years were divided into four groups: FS (n=39), febrile patients wi...
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